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J Clin Pharm Ther. 1992 Dec; 17(6): 369-72.

A drug usage review of omeprazole.

Norris CM, McManus PV, Petty D, Kay EA.

Drug Information and Clinical Services, Harrogate General Hospital, U.K.

A drug use review of omeprazole was carried out at two centres in the Yorkshire Region from December 1990 to April 1991. Data collection documents were used and 66 patients in total were audited. Thirteen patients (19.7%) were treated for indications outside the product licence and 18 patients (27.3%) were treated for longer than 8 weeks. Twenty-eight patients (42.4%) received 40 mg daily. Fifty-one patients (77.3%) had received previous therapy with H2-receptor antagonists and in 33% of these patients it was at an inadequate dose or for an inadequate period of dosing or both. The results indicate a need for a prescribing policy for omeprazole.

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